Dr. Angela Kadenhe-Chiweshe completed her M.D. degree at the Pennsylvania State University College of Medicine. She entered a categorical general surgery residency at the University of Rochester where her interest in pediatric surgery was solidified. In 2001 she joined the Pediatric Tumor Biology Laboratory as a postdoctoral research fellow under the tutelage of Drs. Jessica Kandel and Darrell Yamashiro. During this time she studied the effects of anti-angiogenic therapy in experimental models of pediatric solid tumors. This work led to key discoveries of how these tumors respond to anti-angiogenic therapy and served as important preclinical data for the Phase II studies for Avastin® (bevacizumab). She also concurrently completed a clinical fellowship in Extra-Corporal Membrane Oxygenation with Dr. Charles Stolar. She went on to complete her general surgery training at Columbia University in 2007, and followed with a clinical fellowship in Pediatric Surgery at the Morgan Stanley Children's' Hospital of New York Presbyterian, in 2009. Dr. Chiweshe joined the faculty of the College of Physicians and Surgeons, Columbia University, as Assistant Professor of Surgery in July 2009 until her departure in June 2018, when she briefly joined the Faculty of the Department of Surgery at Westchester Medical Center. Dr. Chiweshe's clinical interests include all aspects of general and thoracic pediatric surgery: in particular, neonatal anomalies, intestinal rehabilitation, hepatobiliary disease, pediatric cancer and vascular anomalies. Dr. Chiweshe's academic interests lie in the field of clinical and translational research. She served as co-PI of the Pediatric Tumor Biology Lab at Columbia, working alongside her mentor Dr. Yamashiro to elucidate the response of the tumor microenvironment of experimental models of pediatric solid tumors to NOTCH inhibition and high dose radiation. She has received grant funding from various sources, throughout her career, including NIH, Pediatric Cancer Foundation, and other institutional and philanthropic sources. Dr. Kadenhe-Chiweshe is a highly respected mentor and teacher, and has served as a role model to many students, residents, and fellows.

Dr. Chiweshe is a Fellow of American College of Surgeons, a member of the American Pediatric Surgical Association, Children's Oncology Group, and the American Academy of Pediatrics. She has been recognized by Castle Connolly as one of "America's Top Doctors".