Darrell J. Yamashiro, MD

Darrell J. Yamashiro, MD Specialties: Pediatrics, Cancer Care, Pediatric Hematology-Oncology

Darrell J. Yamashiro, MD
Specialties: Pediatrics, Cancer Care, Pediatric Hematology-Oncology
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One of America's Top Doctors - Castle Connolly Top Doctors
Rated one of New York Magazine's Best Doctors


CUIMC/Herbert Irving Pavilion
161 Fort Washington Avenue
New York, NY 10032

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Insurances Accepted

Please contact the doctor's office to verify that your insurance is accepted.

  • Affinity Health Plan
  • Amida Care
  • Emblem/GHI
  • Emblem/Hip
  • Empire Blue Cross Blue Shield Healthplus
  • Empire Blue Cross/Blue Shield
  • Fidelis Care
  • Healthfirst
  • Local 1199
  • Magnacare (National)
  • Medicare
  • Multiplan
  • MVP Health Care
  • Oxford Health Plans
  • Quality Health Management
  • UnitedHealthcare
  • WellCare

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About Darrell J. Yamashiro, MD

I am a pediatric oncologist who specializes in caring for children with solid tumors, especially neuroblastoma, Wilms' and other kidney tumors, and liver tumors such hepatoblastoma and hepatocellular carcinoma. I serve as chief of the Division of Hematology, Oncology and Stem Cell Transplantation at Columbia University Irving Medical Center and NewYork-Presbyterian Morgan Stanley Children's Hospital.

I treat children of all ages, from infants to young adults. Some of the cancers I treat are rare (liver tumors account for one to two percent of childhood cancers), but they can be very complex and require a multidisciplinary approach so patients have the best outcomes. I enjoy working as part of a team of physicians, nurse practitioners, nurses, social workers, child life specialists, and other dedicated professionals who care deeply about our patients and provide care with compassion and comfort.

I also conduct basic science research. The latest advances in tumor genetics and the design of innovative therapies make this a very exciting time for cancer research. My team and I have done extensive research on the genetics of hepatoblastoma. We have developed mouse models of this disease and are entering a new phase where we are offering a personalized/precision medicine approach to children with this disease. We are also identifying novel genes that specifically target neuroblastoma—information that may be used to create targeted therapies.

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center
  • NewYork-Presbyterian Morgan Stanley Children's Hospital


  • Angiogenesis

  • Hepatoblastoma

  • Neuroblastoma

  • Pediatric Liver Cancer

  • Pediatric Solid Tumors

  • Wilm's Tumor


  • Fellowship: Children's Hospital of Philadelphia
  • Internship: Children's Hospital of Philadelphia
  • Residency: Children's Hospital of Philadelphia

Board Certifications

  • Pediatric Hematology-Oncology
  • Pediatrics