Geoffrey S. Pitt, MD, PhD Specialties: Cardiovascular Disease

Dr. Pitt's research program has focused on the regulation in excitable cells of internal calcium, the ultimate signal of membrane excitability. He has discovered and described multiple mechanisms that control Ca2+ influx through voltage-gated Ca2+ channels and feedback mechanisms by which internal calcium regulates other channels that influence Ca2+ channel function. The work has entailed structure-function analyses of ion channels and their regulatory subunits and studies of mutations that lead to inherited channelopathies that underlie cardiac arrhythmias and epilepsy.