Mark M. Souweidane, M.D.

Mark M. Souweidane, M.D.

Mark M. Souweidane, M.D.
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One of America's Top Doctors - Castle Connolly Top Doctors
Rated one of New York Magazine's Best Doctors


170 William St
New York, NY 10038
Other Locations

Additional Locations for Mark M. Souweidane, M.D.

  • phone icon
    1305 York Avenue
    New York, NY 10021

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Insurances Accepted

Please contact the doctor's office to verify that your insurance is accepted.

  • Aetna - NYP
  • Aetna - Weill Cornell
  • Aetna [Weill Cornell Employee Plan]
  • Affinity [HMO]
  • Affinity Health Plan
  • Emblem Select Care
  • Emblem/Hip
  • Empire Blue Cross Blue Shield [Pathway Enhanced]
  • Empire Blue Cross Blue Shield Healthplus
  • Empire Blue Cross/Blue Shield
  • Empire Blue Cross/Blue Shield Healthplus
  • GHI
  • Health Insurance Plan of NY (HIP)
  • Healthfirst
  • Medicaid
  • Medicare
  • Rockefeller University - CoreSource
  • United Healthcare
  • UnitedHealthcare

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About Mark M. Souweidane, M.D.

Mark M. Souweidane, MD has dedicated his career to the surgical treatment of children with brain and spinal disorders. His talents as a surgeon are paralleled by a caring attitude and time commitment to patients and their families. That Weill Cornell Medicine is a recognized leader in Pediatric Neurosurgery is a direct result of his recruitment in 1995 and his ongoing devotion to contemporary surgical techniques and investigative endeavors. Specialized surgical skills have gained him international reputation for specific procedures, including removal of intraventricular brain tumors, management of pineal region tumors, treatment of congenital cysts, and surgery for Chiari malformation. In addition to the development of a world-class Pediatric Neurosurgery service, he has championed minimal access neurosurgery. His publications, clinical case volume, and practical courses continue to draw patients and practitioners that benefit from his endoscopic talents. His commitment to the education of future pediatric neurosurgeons is reflected in his participation on the Committee of Admissions for the medical college, his lectures to medical school students, his role as resident advisor, and resident mentoring at one of the country's premier training programs. Surgical areas of expertise include:

>> Removal of intraventricular brain tumors

>> Endoscopic intracranial surgery

>> Tumors(colloid cyst, benign astrocytoma)

>> Hydrocephalus(endoscopic third ventriculostomy)

>> Congenital cysts (endoscopic fenestration)

>> Treatment for Chiari malformations and syringomyelia

>> Management of pineal region tumors

>> Removal of intramedullary spinal cord tumors

>> Correction of craniofacial disorders

>> Multidisciplinary treatment of pediatric vascular abnormalities (arteriovenous malformations, Moyamoya disease, and cavernous malformations)

Dr. Souweidane currently serves as the Vice Chairman of the Department of Neurological Surgery and the Director of Pediatric Neurological Surgery at the Weill Cornell Medical College and Memorial Sloan-Kettering Cancer Center. He is a professor in Neurological Surgery and Pediatrics.


Dr. Souweidane sees patients at four offices:
Upper East Side: Starr
520 East 70th Street (east of York Avenue)
Starr Pavillion, Room 651
New York, NY

Upper East Side: Weill Greenberg
1305 York Avenue (at 70th Street)
Brain and Spine Center, 9th Floor
New York, NY
Please confirm the location of your appointment with your patient coordinator.


Dr. Mark M. Souweidane completed his undergraduate training at the University of Michigan where he graduated with distinction in Microbiology. He attended Wayne State University Medical School as a member of the Alpha Omega Alpha Honor Society. His general surgery internship was completed at University of Michigan Hospitals and he subsequently did his neurosurgery residency at New York University under the direction of Drs. Joseph Ransohoff and Fred Epstein. He served as the chief clinical fellow for pediatric neurosurgery at the Hospital for Sick Children in Toronto during Harold Hoffman's tenure as chairman.

He has gained international acclaim in minimally invasive endoscopic neurosurgery for the treatment of hydrocephalus, intraventricular brain tumors, colloid cysts, and congenital cysts. His other areas of expertise include brain and spinal cord tumors of childhood, Chiari malformations, congenital spinal disorders, arachnoid cysts, and pediatric vascular disorders. His commitment to advanced surgical therapy for children with brain tumors is exemplified by his appointment as Chairman of the Neurosurgery Committee of the Children's Oncology Group. He is a member of the Professional Advisory Board of the Children's Brain Tumor Foundation. He has published 60 peer reviewed articles, authored 6 book chapters, and serves on the editorial board of the journal Neurosurgery. He is the principal investigator of a laboratory that is partly funded by the Pediatric Brain Tumor Foundation. His laboratory focuses on improving the outcome of children with brain tumors by studying experimental local delivery and brain tumor modeling.

Castle Connolly Top Doctors 2016


Weill Cornell Pediatric Brain and Spine Center

Dr. Souweidane's Neuro-oncology Laboratory

Information for Parents

The Children's Brain Tumor Project

Hospital Affiliations

  • NewYork-Presbyterian / Weill Cornell Medical Center
  • NewYork-Presbyterian Komansky Children's Hospital
  • NewYork-Presbyterian Lower Manhattan Hospital


  • Arnold Chiari Malformation

  • Colloid Cysts

  • Craniofacial Abnormalities

  • Craniofacial Disorders

  • Endoscopic Neurosurgery

  • Hydrocephalus

  • Laser Surgery

  • Minimally Invasive Brain Surgery

  • Minimally Invasive Surgery

  • Moya Moya Syndrome

  • Pediatric Brain Tumors

  • Pediatric Epilepsy Surgery

  • Pediatric Neuro-Oncology

  • Pediatric Neurosurgery

  • Pediatric Seizures

  • Pineal Region Tumors

  • Second Opinion

  • Spinal Cord Tumor

  • Stereotactic Surgery

  • Tethered Cords


  • Fellowship: Hospital for Sick Children
  • Internship: University of Michigan Hospitals
  • Medical School: Wayne State University School of Medicine
  • Residency: New York University Medical Center

Board Certifications

  • Neurological Surgery

Languages Spoken

  • English

awards iconawards icon

  • Alpha Omega Alpha Inductee, 1988
  • Bachelors of Science Degree with High Honors, 1983
  • Beez Foundation Research Grant, 2005-2006
  • Beez Foundation Research Grant, 2010
  • Brain Tumor Foundation Award, 2016
  • Breakthrough Spirit Award, Childrens Cancer & Blood Foundation, 2016
  • Castle Connolly Best Doctors (nationwide), 2010-2015
  • Castle Connolly Top Doctors (New York Metro Area), 2004-2019
  • Chiari & Syringomyelia Foundation Award, 2015
  • Childrens Brain Tumor Foundation, Project Program Grant, 2000
  • Childrens Hope Award, 2007
  • Clinical & Translational Science Center Pilot Award, 2008
  • Consumers Research Council of America Top Surgeons Award, 2010
  • Cristian Rivera Foundation Vison of Hope Award, 2016
  • Cristian Rivera Vision of Hope Award, 2012, 2013, 2014
  • Cristian Rivera Vision of Hope Award, 2014
  • Dana Neuroimmnology Foundation, 2010
  • Emily Dorfman Foundation for Children, 2001-2003
  • Employee of the Year for Department of Neurological Surgery (NYPH-WMC), 2010, 2011
  • Isabel Gloria Neidorf Research Grant, 2004-2007
  • James B. Angell Scholar Recipient, 1982, 1983
  • Lehman Brothers Foundation Award, 2006-2009
  • Louis and Rachel Rudin Foundation, Inc., 2012-2014
  • McKenna Claire Foundation Research Grant, 2014
  • Medical Doctorate Degree with Distinction, 1988
  • New York Magazines Best Doctors, 2012-2014
  • New York Magazines Best Doctors, 2016
  • New York SuperDoctors 2008, 2009, 2012-2019
  • Nina W. Werblow Charitable Trust Award, 2009
  • Pediatric Brain Tumor Foundation Research Grant, 2007-2008
  • Resident Teaching Award, Department of Neurological Surgery (NYPH-WMC), 2004, 2005
  • Save a Childs Heart Foundation, 2003
  • St. Baldricks Foundation, 2010
  • The Cristian Rivera Foundation Award, 2010
  • The Cure Starts Now Foundation Research Grant, 2010
  • TSC NYC Marathon Finisher: 5:05:44, 2018