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Dr. Barr's research focuses on respiratory epidemiology and particularly on chronic obstructive pulmonary disease (COPD) and emphysema. He is interested in a better understanding of the causes of emphysema and COPD subtypes beyond smoking and uses machine learning/artificial intelligence to integrate advanced imaging (computed tomography [CT] and magnetic resonance imaging [MRI]) with multi-omic measures in large cohorts. He is principal investigator (PI) of the Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study, the longest-running prospective study of emphysema on CT; the SPIROMICS Heart Failure Study, a large study of cardiopulmonary interactions using state-of-the-art echocardiograp...