Dr. Sarah Flanagan Wesley graduated from medical school at the Royal College of Surgeons in Dublin, followed by residency in adult neurology at the Icahn School of Medicine at Mount Sinai and then fellowship in neuroimmunology at the Yale School of Medicine. Dr. Wesley was on faculty at Yale as an Assistant Professor of Neurology in the neuroimmunology subdivision until joining faculty at Columbia in 2020.

Dr. Wesley treats a range of neuroimmunological and autoimmune neurological conditions, including various forms of autoimmune encephalitis, CNS vasculitis, neuro-rheumatological conditions, multiple sclerosis, and immune-related toxicity to cancer treatments.

Dr. Wesley serves as a lead for Columbia's neurological immunotoxicity program, conducting clinical and translational research on the mechanisms and management of neurological side effects to cancer treatments, such as cancer immune checkpoint inhibitors and CAR T-cell therapy.